NOT KNOWN FACTUAL STATEMENTS ABOUT LIMITED EDITION EXCLUSIVE LSD CRYSTAL)

Within the LSD-bound crystal framework, the aspect chain of your lid residue L209EL2 sorts in depth hydrophobic contacts with the two LSD and bordering residues in TMs III, IV, and V (Determine 4C). When the lid moved aside to show the binding pocket in simulation, various of those contacts broke. We So hypothesized that L209EL2 acts to be a latch,